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1- Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
2- Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
3- Mashhad University of Medical Sciences, Mashhad, Iran.
4- Mashhad University of Medical Sciences, Mashhad, Iran. , Khademigh@mums.ac.ir
Abstract:   (60 Views)
Background: Pediatric Intensive Unit (PICU) admitted patients are considered as a nutritionally high-risk population in whom optimum energy and nutrient delivery is an important treatment strategy preventing organ disfunction and subsequently poor clinical outcomes.
Objectives: The present study aimed to investigate the nutritional adequacy indices and their probable relations to clinical outcomes in critically ill children.
Methods: This project was a retrospective cross-sectional study carried out at the Akbar Children's Hospital, Mashhad, Iran. All critically ill children with PICU stay >48 hours during May-June 2019 were enrolled. Age, gender, medical diagnosis, nutritional status, energy and protein requirements and deliveries, and clinical outcomes of patients were extracted.
Results: Seventy-one patients were included, among whom 39 subjects (54.9%) were male. The prevalence of malnutrition was 45.3% and 52.4% in PICU patients with surgical and non-surgical underlying diseases, respectively. There were significant associations among nutritional status of the patients (upon the PICU admission time), infection, and mortality rate. Mean ± SEM values of the estimated energy requirement and delivered energy were as 85.7±1.6 and 68.3±2.1 Kcal/kg/d, respectively. In addition, the estimated protein requirement and delivered protein were 2.5±0.08 and 1.8±0.03 gr/kg/d, respectively. Energy intake had a negative association with infection rate and lower protein delivery was negatively associated with prolonged length of stay on mechanical ventilation.
Conclusion: Significant associations between energy/protein delivery and some clinical outcomes were shown. The findings indicate the necessity of immediate further studies on different nutritional interventions efficacy as well as monitoring of optimal nutrition support barriers in critically ill children.
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Type of Study: Original Article | Subject: Pediatric Intensivist
Received: 2021/08/4 | Accepted: 2021/11/8

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