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1- Pediatric Intensivist, Department of Pediatrics, Mashhad University of Medical Sciences, Mashhad, Iran.
2- Pediatric Intensivist, Neonatal research center, Mashhad University of Medical Sciences, Mashhad, Iran
3- Clinical Research Development Unit of Akbar Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
4- Pulmonary fellowship, Internal department, Mashhad University of Medical Sciences, Mashhad, Iran.
5- Assistant Professor of Pediatric Intensive Care, Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical sciences, Mashhad, Iran. , sezavardm@mums.ac.ir
Abstract:   (175 Views)
Background: COVID-19 is a highly infectious and contagious disease. Since the outbreak of COVID-19, most studies on children have focused on the incidence and prognosis of the disease and the number of studies on the epidemiological characteristics of the disease is much less. The aim of this study was to investigate some epidemiological aspects of the disease in children with COVID-19.
Method: This study examined children under 18 years with COVID-19 who were hospitalized in hospitals in the North East of Iran from the beginning of the outbreak until the end of September 2020. Information was collected from patients' records and interviews with parents. Demographic data, history of diseases and taking medicine in children, educational, occupational, and smoking status in parents, patients’ residence conditions and any report of COVID-19 in patients' family and relative were recorded.
Results: Of the 107 children, 57% were male, and 52.3% had no underlying disease. The mean age of patients was 67 months. Average weight of children was 20.36 ± 13.75 kilograms and the average length of hospital stay was 9±8 days. Multisystem inflammatory syndrome in children (MIS-C) was observed in 34.6% of patients and its relationship with death was highly significant (p-value: 0.001). Length of hospital stay was influenced by history of medication consumption (p-value: 0.013) and underlying disease (p-value: 0.001) and its increase was associated with increased risk of MIS-C (p-value:0.032) and death (p-value:0.047).
Conclusion: Male sex, length of hospital stay, and MIS-C were identified as risk factors associated with worsening of the outcome of COVID-19 disease in children.
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Type of Study: Original Article | Subject: Infectious Diseases
Received: 2021/03/28 | Accepted: 2021/07/25

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