Volume 9, Issue 3 (7-2021)                   J. Pediatr. Rev 2021, 9(3): 239-246 | Back to browse issues page


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Karami H, Beyzaee A M, Masiha F, Ghasemi M, Nosrati A, Mousavi S A et al . Digital Clubbing and Hodgkin Disease in Children: A Case Report and Review of Literature. J. Pediatr. Rev. 2021; 9 (3) :239-246
URL: http://jpr.mazums.ac.ir/article-1-347-en.html
1- Thalassemia Research Center (TRC), Hemoglobinopathy Institute, Mazandaran University of Medical Sciences, Sari, Iran.
2- Student Research Committe, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
3- Pediatric Infectious Diseases Research Center, Communicable Disease Institute, Mazandaran University of Medical Sciences, Sari, Iran.
4- Immunogenetics Research Center, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
5- Department of Pathology, Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Iran.
6- Department of Pediatric Surgery, Pediatric Infectious Diseases Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
7- Thalassemia Research Center (TRC), Hemoglobinopathy Institute, Mazandaran University of Medical Sciences, Sari, Iran. , dr.naderisorki@gmail.com
Abstract:   (1115 Views)
Introduction: Digital clubbing (hypertrophic osteoarthropathy) as the initial presentation of lymphoma is rarely reported, particularly in children. In this study, we report a patient with intrathoracic Hodgkin Disease (HD) and digital clubbing as the first presentation, and we will review the literature regarding the same condition. 
Case Presentation: A 10-year-old boy presented with a 2-month history of cough, mild dyspnea, and night sweats, with prominent digital clubbing. A chest x-ray and a computed tomography scan of the chest showed multiple mediastinal masses. A mediastinal lymph node biopsy was done. Pathologic examination was indicative of nodular sclerosis HD.
Conclusions: In patients with digital clubbing, intrathoracic malignancies should be considered a differential diagnosis and must be ruled out by precise examination and paraclinical help.
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Type of Study: Case Report and Review of Literature | Subject: Pediatric Hematology and Oncology
Received: 2020/07/10 | Accepted: 2020/11/18 | Published: 2021/07/1

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