Journal of Pediatrics Review

Published by: Kowsar

Management of Psoriasis in Children: a Narrative Review

Zohreh Hajheydari 1 , * , Leila Sarparast 2 and Soheila Shahmohammadi 3
Authors Information
1 Department of Dermatology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, IR Iran
2 Clinical Research Development Unit, Bou Ali Sina Hospital, Mazandaran University of Medical Sciences, Sari, IR Iran
3 Antimicrobial Resistant Nosocomial Infection Research Center, Mazandaran University of Medical Sciences, Sari, IR Iran
Article information
  • Journal of Pediatrics Review: January 31, 2015, 3 (1); e131
  • Published Online: January 20, 2015
  • Article Type: Review Article
  • Received: November 20, 2014
  • Revised: November 25, 2014
  • Accepted: November 30, 2014
  • DOI: 10.5812/jpr.131

To Cite: Hajheydari Z, Sarparast L, Shahmohammadi S. Management of Psoriasis in Children: a Narrative Review, J Pediatr Rev. 2015 ;3(1):e131. doi: 10.5812/jpr.131.

Copyright © 2015, Mazandaran University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Context
2. Evidence Acquisition
3. Results
4. Conclusions
  • 1. Cordoro KM. Management of childhood psoriasis. Adv Dermatol. 2008; 24: 125-69[PubMed]
  • 2. Huerta C, Rivero E, Rodriguez LA. Incidence and risk factors for psoriasis in the general population. Arch Dermatol. 2007; 143(12): 1559-65[DOI][PubMed]
  • 3. Schon MP, Boehncke WH. Psoriasis. N Engl J Med. 2005; 352(18): 1899-912[DOI][PubMed]
  • 4. Darley CR, Cunliffe WJ, Green CM, Hutchinson PE, Klaber MR, Downes N. Safety and efficacy of calcipotriol ointment (Dovonex) in treating children with psoriasis vulgaris. Br J Dermatol. 1996; 135(3): 390-3[PubMed]
  • 5. Dogra S, Kaur I. Childhood psoriasis. Indian J Dermatol Venereol Leprol. 2010; 76(4): 357-65[DOI][PubMed]
  • 6. Swanbeck G, Inerot A, Martinsson T, Enerback C, Enlund F, Samuelsson L, et al. Genetic counselling in psoriasis: empirical data on psoriasis among first-degree relatives of 3095 psoriatic probands. Br J Dermatol. 1997; 137(6): 939-42[PubMed]
  • 7. Benoit S, Hamm H. Childhood psoriasis. Clin Dermatol. 2007; 25(6): 555-62[DOI][PubMed]
  • 8. Henseler T. The genetics of psoriasis. J Am Acad Dermatol. 1997; 37(2)[DOI]
  • 9. Di Meglio P, Villanova F, Nestle FO. Psoriasis. Cold Spring Harb Perspect Med. 2014; 4(8)[DOI][PubMed]
  • 10. Honig PJ. Guttate psoriasis associated with perianal streptococcal disease. J Pediatr. 1988; 113(6): 1037-9[PubMed]
  • 11. Johnson TM, Duvic M, Rapini RP, Rios A. AIDS exacerbates psoriasis. N Engl J Med. 1985; 313(22): 1415[PubMed]
  • 12.
  • 13. Treating psoriasis in children. 1996;
  • 14. Leman J, Burden D. Psoriasis in Children. Paediatr Drugs. 2001; 3(9): 673-80[DOI]
  • 15. Griffiths CEM, Barker J. W. N. . Rook's text book of Dermatology. 2010; 20: 16-20
  • 16. Morris A, Rogers M, Fischer G, Williams K. Childhood psoriasis: a clinical review of 1262 cases. Pediatr Dermatol. 2001; 18(3): 188-98[PubMed]
  • 17. Liao PB, Rubinson R, Howard R, Sanchez G, Frieden IJ. Annular pustular psoriasis--most common form of pustular psoriasis in children: report of three cases and review of the literature. Pediatr Dermatol. 2002; 19(1): 19-25[PubMed]
  • 18. Roberton DM, Cabral DA, Malleson PN, Petty RE. Juvenile psoriatic arthritis: followup and evaluation of diagnostic criteria. J Rheumatol. 1996; 23(1): 166-70
  • 19. de Jager ME, de Jong EM, van de Kerkhof PC, Seyger MM. Efficacy and safety of treatments for childhood psoriasis: a systematic literature review. J Am Acad Dermatol. 2010; 62(6): 1013-30[DOI][PubMed]
  • 20. Oranjea AP, Marcouxb D, Svenssonc A, Prendivilled J, Krafchike B, Toolef J, et al. Topical calcipotriol in childhood psoriasis. Journal of the American Academy of Dermatology. 1997; 36(2): 203-8[DOI]
  • 21. Capella GL, Finzi AF. Psoriasis and other papulosquamous diseases in infants and children. Clin Dermatol. 2000; 18(6): 701-9[PubMed]
  • 22. Dermatology. 2012; : 148-150
  • 23. Ortonne JP, van de Kerkhof PC, Prinz JC, Bieber T, Lahfa M, Rubins A, et al. 0.3% Tacrolimus gel and 0.5% Tacrolimus cream show efficacy in mild to moderate plaque psoriasis: Results of a randomized, open-label, observer-blinded study. Acta Derm Venereol. 2006; 86(1): 29-33[DOI][PubMed]
  • 24. Wohlrab J. Basistherapie der Psoriasis vulgaris. Der Hautarzt. 2006; 57(8): 661-5[DOI]
  • 25. Steele JA, Choi C, Kwong PC. Topical tacrolimus in the treatment of inverse psoriasis in children. J Am Acad Dermatol. 2005; 53(4): 713-6[DOI][PubMed]
  • 26. Yamamoto T, Nishioka K. Topical tacrolimus is effective for facial lesions of psoriasis. Acta Derm Venereol. 2000; 80(6): 451[PubMed]
  • 27. Zvulunov A, Anisfeld A, Metzker A. Efficacy of short-contact therapy with dithranol in childhood psoriasis. Int J Dermatol. 1994; 33(11): 808-10[PubMed]
  • 28. Busch AL, Landau JM, Moody MN, Goldberg LH. Pediatric psoriasis. Skin Therapy Lett. 2012; 17(1): 5-7[PubMed]
  • 29. Maverakis E, Miyamura Y, Bowen MP, Correa G, Ono Y, Goodarzi H. Light, including ultraviolet. J Autoimmun. 2010; 34(3)-57[DOI][PubMed]
  • 30. Osorio F, Magina S. Phototherapy and photopheresis: old and new indications. Expert Rev Dermatol. 2011; 6(6): 613-23[DOI]
  • 31. Pugashetti R, Koo J. Phototherapy in pediatric patients: choosing the appropriate treatment option. Semin Cutan Med Surg. 2010; 29(2): 115-20[DOI][PubMed]
  • 32. Racz E, Prens EP, Kant M, Florencia E, Jaspers NG, Laman JD, et al. Narrowband ultraviolet B inhibits innate cytosolic double-stranded RNA receptors in psoriatic skin and keratinocytes. Br J Dermatol. 2011; 164(4): 838-47[DOI][PubMed]
  • 33. Lara-Corrales I, Ramnarine S, Lansang P. Treatment of childhood psoriasis with phototherapy and photochemotherapy. Clin Med Insights Pediatr. 2013; 7: 25-33[DOI][PubMed]
  • 34. Judge MR, McDonald A, Black MM. Pustular psoriasis in childhood. Clin Exp Dermatol. 1993; 18(2): 97-9[PubMed]
  • 35. Glover MT, Peters AM, Atherton DJ. Surveillance for skeletal toxicity of children treated with etretinate. Br J Dermatol. 1987; 116(5): 609-14[PubMed]
  • 36. Paller AS. Dermatologic uses of methotrexate in children: indications and guidelines. Pediatr Dermatol. 1985; 2(3): 238-43[PubMed]
  • 37. Juanqin G, Zhiqiang C, Zijia H. Evaluation of the effectiveness of childhood generalized pustular psoriasis treatment in 30 cases. Pediatr Dermatol. 1998; 15(2): 144-6[PubMed]
  • 38. Alli N, Gungor E, Karakayali G, Lenk N, Artuz F. The use of cyclosporin in a child with generalized pustular psoriasis. Br J Dermatol. 1998; 139(4): 754-5[PubMed]
  • 39. Paller AS, Siegfried EC, Langley RG, Gottlieb AB, Pariser D, Landells I, et al. Etanercept treatment for children and adolescents with plaque psoriasis. N Engl J Med. 2008; 358(3): 241-51[DOI][PubMed]
  • 40. Papoutsaki M, Costanzo A, Mazzotta A, Gramiccia T, Soda R, Chimenti S. Etanercept for the treatment of severe childhood psoriasis. Br J Dermatol. 2006; 154(1): 181-3[DOI][PubMed]
  • 41. Pereira TM, Vieira AP, Fernandes JC, Antunes H, Basto AS. Anti-TNF-alpha therapy in childhood pustular psoriasis. Dermatology. 2006; 213(4): 350-2[DOI][PubMed]
  • 42. Farnsworth NN, George SJ, Hsu S. Successful use of infliximab following a failed course of etanercept in a pediatric patient. Dermatol Online J. 2005; 11(3): 11[PubMed]
  • 43. Menter MA, Cush JM. Successful treatment of pediatric psoriasis with infliximab. Pediatr Dermatol. 2004; 21(1): 87-8[PubMed]
  • 44. Weishaupt C, Metze D, Luger TA, Stander S. Treatment of pustular psoriasis with infliximab. J Dtsch Dermatol Ges. 2007; 5(5): 397-9[DOI][PubMed]
  • 45. Patrizi A, Costa AM, Fiorillo L, Neri I. Perianal streptococcal dermatitis associated with guttate psoriasis and/or balanoposthitis: a study of five cases. Pediatr Dermatol. 1994; 11(2): 168-71[PubMed]
  • 46. Pacifico L, Renzi AM, Chiesa C. Acute guttate psoriasis after streptococcal scarlet fever. Pediatr Dermatol. 1993; 10(4): 388-9[PubMed]
  • 47. Rosenberg EW, Noah PW, Zanolli MD, Skinner RJ, Bond MJ, Crutcher N. Use of rifampin with penicillin and erythromycin in the treatment of psoriasis. Preliminary report. J Am Acad Dermatol. 1986; 14(5 Pt 1): 761-4[PubMed]
  • 48. Vincent F, Ross JB, Dalton M, Wort AJ. A therapeutic trial of the use of penicillin V or erythromycin with or without rifampin in the treatment of psoriasis. J Am Acad Dermatol. 1992; 26(3): 458-61[DOI]
  • 49. Burden AD. Management of psoriasis in childhood. Clin Exp Dermatol. 1999; 24(5): 341-5[PubMed]
  • 50. Perez-Barrio S, Careaga JM. [Etanercept in childhood psoriasis]. Actas Dermosifiliogr. 2010; 101: 50-4[DOI]
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