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Context : Fluoride is a necessary element for bone growth and prevention of dental caries. Diet and dentifrices are the most significant sources of fluoride exposure in children. The concentration of fluoride differs in various types of foods. In optimal levels, fluoride has beneficial effects on dental health but also has some adverse effects in high concentrations. Nowadays, the uncontrolled consumption of fluoride containing products can leads to fluoride poisoning which is associated with  various structural and functional defects in different organs. The aim of our study was to review the previous studies on fluoride toxicity and also provide suitable informations to dentists and specialists about fluoride safety in children.
Evidence acquisition: The data we used in our review were searched from articles published until 2019 and collected from official web pages and documents published from different international institutions. Topics which discussed in this review were dietary intake of fluoride, fluoride metabolism, history of fluoride use, mechanism of fluoride action, overuse and toxicity of fluoride. After the abstract screening, we recalled relevant studies for full-text review.
Results: Fluoride is generally found in human daily diet. There are different sources of fluoride such as fluoride supplements or fluoride dentifrices. Fluoride also has a topical protective effect against teeth decay. Ingestion of high doses of fluoride in a short period of time can lead to fluoride poisoning. This problem usually happens in children while they are using products for oral hygiene such as fluoridated toothpaste and can threaten their overall health.
Conclusion:Although the intake of high doses of fluoride has some adverse health effects, its topical use is considered safe. Fluoride can improve childrens dental health in different ways such as preventing caries.

Full-Text [PDF 885 kb]   (46 Downloads)    
Type of Study: Narrative Review | Subject: Pediatrics
Received: 2019/12/23 | Accepted: 2020/09/5

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